Lewy Body Dementia Promotion by Air Pollutants

Science, 2025

This groundbreaking study shows how long-term exposure to fine particulate air pollution (PM₂.₅) increases the risk of Lewy body dementia in humans. Using both population data and mouse models, the team demonstrates that pollutants can trigger toxic α-synuclein strains that mimic human disease.

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Blocking the Self-Destruct Program of Dopamine Neurons