Blocking the Self-Destruct Program of Dopamine Neurons

Written By Dawson Lab

Movement Disorders, 2024

This translational study highlights a new therapeutic target for Parkinson’s disease: inhibiting the nuclease activity of macrophage migration inhibitory factor (MIF). By blocking this “executioner” enzyme, the authors show protection of dopamine neurons from self-destruction.

Dawson Lab https://www.thedawsonlab.org
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