Parthanatos: Mechanisms, Modulation, and Therapeutic Prospects

Review, 2024

A comprehensive review of parthanatos, a unique form of programmed cell death discovered by the Dawson Lab. This article synthesizes two decades of research, detailing molecular mechanisms and exploring how targeting this pathway may lead to treatments for stroke and neurodegeneration.

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Blocking the Self-Destruct Program of Dopamine Neurons

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A Nuclease that Mediates PARP-1–Induced Cell Death